Is that hit a real binder — or an aggregation artifact?
Every hit list carries this hidden question. At hit-list scale, most teams cannot answer it compound by compound: standard solubility workflows are too slow, too material-intensive, and often reduced to single-point checks. So aggregators slip into biophysical assays looking like binders, shifting apparent affinities and creating artifacts that send teams into retesting and follow-up.
The ORYL F1 changes the triage step. It is a high-throughput, low-compound, plate-based solubility and aggregation profiling instrument, powered by Ultrafast Light Scattering (ULS).