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Applications

Browse Our Applications

From early discovery screening to formulation profiling, the ORYL F1 delivers decision-ready solubility and aggregation results across a wide range of applications — explore to see how the ORYL F1 can support your workflow.

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Established

Fully validated, customer-anchored use-cases where the ORYL F1 is already delivering value in pharma R&D pipelines — see Application Notes for details.

In Development

Applications within the ORYL F1’s capabilities that we are actively developing — reach out if you see a fit, we’re always open to new partnerships.

Formulation

Excipient Screening

Screen surfactants, sugars, amino acids, salts, and buffers for small molecule and biologic stabilization at plate scale — matrix sizes traditional methods choke on.

Formulation

High-Concentration Liquid Formulation

Aggregation propensity, viscosity proxies, and formulation ranking at concentrations where DLS saturates and B22 measurement is too slow to scale.

Formulation

Supersaturation Kinetics

Track precipitation kinetics from supersaturated states with fine temporal resolution. Lag phase, nucleation, growth — captured directly.

Discovery

Protein-Protein Interaction

Detect label-free protein-protein / protein-peptide assembly events (binding, conformational ordering, ternary PROTAC complexes) via SHS+LLS signatures.

Formulation

Vaccine Antigen Adsorption

Rank conditions for antigen-on-adjuvant adsorption efficiency, reading the adsorbed protein directly rather than inferring from supernatant depletion.

Formulation

Crystallization & Polymorph Screening

Screen crystallization conditions by monitoring nucleation and crystal-form emergence directly via SHS. No transparency requirement on the matrix.

Application Notes

Detailed application data and workflows are available in our resource library.

Have a specific application in mind?

Discuss your workflow with ORYL and see how the ORYL F1 can support your research.