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Discovery

Protein-Protein Interaction

For Discovery Biology teams characterizing protein-protein interactions

Detect label-free protein-protein / protein-peptide assembly events (binding, conformational ordering, ternary PROTAC complexes) via SHS+LLS signatures.

What changes with the F1

Catch oligomerization other methods miss

SHS picks up ordered assembly even when the size change is small — plate-scale, label-free.

  • Detects ordered assembly via SHS — sensitive even to modest mass changes.
  • Plate-format titration, microliter-scale per condition.
  • No SEC-MALS, AUC, or native MS sample-prep overhead.
FAQ

Common questions about the Supersaturation Kinetics

Complementary SHS and LLS readouts detect the early onset of association and aggregation directly in solution, including at high concentration where DLS saturates.

It is a high-throughput, plate-based, label-free alternative that works in undiluted, concentrated samples where DLS multiple-scattering and SEC dilution limit those methods.

Ready to put the F1 to work on your samples?

De-risk solubility and aggregation in your pipeline — early, with low-compound, plate-based measurement.

Request a Measurement Service
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