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Formulation

Crystallization & Polymorph Screening

For Formulation and Analytical Development teams running crystallization screens

Non-centrosymmetric crystal lattices give a direct SHS signal (no transparency requirement on the matrix), LLS tracks crystal growth in parallel, and it works in opaque/turbid matrices where transmission-based optical methods struggle.

What changes with the F1

Detect nucleation directly

Non-centrosymmetric crystal lattices give a strong direct SHS signal — no transparency requirement on the matrix.

  • Direct nucleation readout via SHS — non-centrosymmetric lattices give a signal.
  • LLS tracks crystal growth in parallel.
  • Works in matrices where optical methods struggle.
graph of Solution and SHS SIgnal; non-centrosymmetric lattice gives a direct SHS signal

Ready to put the F1 to work on your samples?

De-risk solubility and aggregation in your pipeline — early, with low-compound, plate-based measurement.

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