For Formulation and Analytical Development teams running crystallization screens
Non-centrosymmetric crystal lattices give a direct SHS signal (no transparency requirement on the matrix), LLS tracks crystal growth in parallel, and it works in opaque/turbid matrices where transmission-based optical methods struggle.
Non-centrosymmetric crystal lattices give a strong direct SHS signal — no transparency requirement on the matrix.
Second Harmonic Scattering responds to ordered crystalline assembly rather than bulk transmission, so the signal turns on as crystals form — even in suspensions that defeat transmission-based optical methods.
Yes — parallel conditions across solvents, antisolvents, pH and temperature run on a plate, with SHS as the crystal-form emergence readout.
De-risk solubility and aggregation in your pipeline — early, with low-compound, plate-based measurement.