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Formulation

Supersaturation Kinetics

For Pre-formulation and DMPK / DAG teams characterizing precipitation behavior

Track precipitation kinetics from supersaturated states with fine temporal resolution. Lag phase, nucleation, growth — captured directly.

What changes with the F1

Watch precipitation as it happens

Time-series LLS at fine temporal resolution — lag, nucleation, growth in one run.

  • Time-series LLS at fine temporal resolution.
  • Captures nucleation lag and growth kinetics directly.
  • Plate-scale parallel — no per-time-point sub-sampling.
Graph of nucleation showing LAG and equilibrium solubility
FAQ

Common questions about the Supersaturation Kinetics

A time-resolved measurement of how a supersaturated drug solution evolves — tracking the lag phase, nucleation onset and growth — used in pre-formulation and amorphous solid dispersion work.

It reads Second Harmonic Scattering and Linear Light Scattering over time on a plate, detecting the early onset of aggregation and nucleation before turbidity, with about 100x less compound than HPLC-based workflows.

Supersaturation governs whether an enabling formulation stays dissolved long enough to be absorbed; quantifying its kinetics de-risks amorphous solid dispersion and solubility-enhancement decisions early.

Ready to put the F1 to work on your samples?

De-risk solubility and aggregation in your pipeline — early, with low-compound, plate-based measurement.